Effects of Nandrolone Decanoate on Ultrastructure of Testis in Male Adult Rats

نویسندگان

  • H. Mirkhani
  • Seyed Fakhroddin Mesbah
چکیده

Background: To improve the athletic ability and muscle mass, anabolic androgenic steroids are abused by athletes. Little is known about how these compounds affect the fine structures of the testis. This study aimed to identify the changes in the fine structure of testis following administration of nandro-

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Effects of Nandrolone Decanoate on Ultrastructure of Testis in Male Adult Rats

Background: To improve the athletic ability and muscle mass, anabolic androgenic steroids are abused by athletes. Little is known about how these compounds affect the fine structures of the testis. This study aimed to identify the changes in the fine structure of testis following administration of nandrolone decanoate. Methods: Twenty five Sprague-Dawley rats were randomly divided into two expe...

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The Effect of Nandrolone Decanoate on the Body, Testis and Epididymis Weight and Semen Parameters in Adult Male Rats

Background: Anabolic-androgenic steroids are used at high doses by athletes for improving athletic ability, physical appearance and muscle mass. Therefore, the abuse of these steroids has been significantly increased. Many undesirable side effects of these steroids on the male reproductive function have been reported, however, little is known about their effects on sexual behavior and tissues o...

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The effects of swimming exercise and supraphysiological doses of nandrolone decanoate on the testis in adult male rats: a transmission electron microscope study.

Anabolic-androgenic steroids (AAS) are used in high doses by athletes to improve athletic ability, physical appearance, and muscle mass. Unfortunately, the abuse of these agents has significantly increased. It has been established that exercise and high doses of AAS may influence the hypothalamic-pituitary gonadal (H-P-G) axis, which can in turn affect the ultrastructure of the testes. However,...

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P-40: Melatonin Could Improve The Sperm Quality, Level of Antioxidant Enzymes and Lipid Peroxidation of Testis after The Combination of Swimming Exercise and Supraphysiological Dose of Nandrolone Decanoate in Rats

Background: This study investigates the effects of melatonin on the sperm quality, the level of antioxidant enzymes (TAC) and malondialdehyde (MDA) after the combination of swimming exercise and nandrolone decanoate (DECA). Materials and Methods: Two groups of male Wistar rats were treated for eight weeks as follows; group A consist of: CO (control), Sham, N (DECA), S (swimming) and NS (DECA pl...

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Modulatory Effect of Gonadotropins on Rats’ Ovaries after Nandrolone Decanoate Administration: A Stereological Study

Background: Nandrolone decanoate (ND) is an anabolic androgenic steroid (AAS) which influences the ovarian structure and function. We assessed the effects of ND on the ovarian volume, number of primordial follicles, and level of hormones and also evaluated the modulatory effects of gonadotropins on the histopathological changes imposed by the administration of ND. Methods: Six groups of Sprague...

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تاریخ انتشار 2008